| Vitamin D or is That D2, D3? What Should I Use? |
 This topic was inspired by a reader of my blog and I though it deserved a blog post instead of a one line answer. There are many parameters concerning dosing of vitamin D, and each individual will have to apply what fits for them. With that said, here is the take on some aspects of vitamin D dosing that may be helpful to you, or at least I hope it helps you and many others.
Vitamin D is a more complex vitamin, mostly because it is innately manufactured by the human body, therefore it should be considered more of a hormone rather then a vitamin. In trying to keep it as simple as possible without getting into heavy biochemistry and boring everyone to death, here is my simplified take on it.
A brief summary of Vitamin D.
In my formulations I only use D-3 if that might be a question someone is curious about.
1. Vitamin D is manufactured by both plants and animals. Vitamin D3 is particularly found on the skin of animals, as a byproduct of synthesis.
2. Vitamin D is not beneficial in all its forms. Vitamin D2, one of the forms of vitamin D can be toxic to the body. Vitamin D3 is good for the body.
3. You can get vitamin D from fortified foods or supplements. However, vitamin D3 is only available in the form of powders, pills or in liquids. They are rarely found in foods.
4. Supplements for the two vitamins are sourced differently. D2 being plant based, D3, animal based.
5. The D2 form of the vitamin has a shorter shelf life compared to the D3 form.
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| Dosing for adults 18 plus and for what purpose. |
Adults (18 years and older)
Please keep in mind that these doses are not meant to prescribe to anyone. I am not privy to each individuals medical condition and this should only be used as informational to help understand the applications for specific conditions and should only e done under the supervision of a doctor specializing in such.
In Healthy Ride Formulas I mostly use 400IU per serving which is considered 100% of the RDA in normal cases for overall use. If a person used it twice per day it would be double (800IU)
Vitamin D is included in most multivitamins, usually in strengths from 50 IU to 1,000 IU (international units), as softgels, capsules, tablets,liquids or powders. Since 2000, discrepancies have arisen regarding the benefits of vitamin D and how much is sufficient. Safety research supports an upper limit of a dose of vitamin D to be more than or equal to 250 micrograms daily (10,000 IU of vitamin D3).
The Institute of Medicine (IOM) has reviewed and updated the Dietary Reference Intakes (DRIs). The IOM found that there is strong evidence to support the use of vitamin D with calcium for bone health but that it was lacking for other health conditions.
The new recommended daily allowance (RDA), as set in 2010, is based on age, as follows: for those 1-70 years of age, 600 IU daily; for those 71 years and older, 800 IU daily; and for pregnant and lactating women, 600 IU daily. This level can be achieved through substantial daily skin exposure to sunlight and only takes about 10 minutes.
Not all doses have been found to be effective for conditions that have been studied.
For deficiency, at least 1,000 IU (25 micrograms) of vitamin D has been taken by mouth daily (or 8,400 IU of vitamin D3 weekly). Other doses that have been studied include 50,000 IU daily for six weeks, 300,000 IU of oral vitamin D3 three times a year, 800 IU daily in combination with calcium, 400 IU daily, and 300,000 IU every three months. 300,000 IU of vitamin D has been used intramuscularly as bolus dose of vitamin D2 or D3, three times per year, and 600,000 IU (15 milligrams) of vitamin D has been used as single injections.
For anticonvulsant-induced osteomalacia, 2,000 IU of vitamin D2 has been taken by mouth daily plus 390 milligrams of calcium lactate daily for three months.
For cancer prevention, individuals taking 1,000 IU of oral vitamin D daily had a lower incidence of colon cancer.
For cardiovascular disease, 1,000 IU of vitamin D has been taken by mouth daily. Other doses that have been taken include approximately 528 IU of vitamin D2 or D3 daily.
For cognition, 528 IU of vitamin D2 or D3 has been taken by mouth daily.
For diabetes (type 2), 400-5714 IU of vitamin D has been taken by mouth daily (with or without calcium) for two months to seven years.
For fall prevention, more than 200-1,200 IU of vitamin D has been taken by mouth daily.
For fracture prevention, 400-1,100 IU of vitamin D has been taken by mouth daily, 100,000 IU of vitamin D2 has been taken by mouth every four months for 36 months, or 10 micrograms of vitamin D3 has been taken by mouth daily for 24 months. For fracture prevention, 300,000 IU of vitamin D2 every 12 months has been used intramuscularly for 36 months.
For hypertension (high blood pressure), 400-8,571 IU of vitamin D has been taken by mouth daily (with or without calcium) for various durations.
For hypocalcemia, 0.25 micrograms of calcitriol has been taken by mouth daily, and dosing may be increased by 0.25 micrograms daily at 4-8-week intervals.
For hypoparathyroidism, dihydrotachysterol has been taken by mouth at an initial dose of 750 micrograms (0.75 milligrams) to 2.5 milligrams daily for several days. A maintenance dose of 0.2-1 milligram has been taken by mouth daily. Ergocalciferol has been taken by mouth at a dose of 50,000-200,000 IU daily along with four grams of calcium lactate, six times daily.
For immunomodulation, the following doses have been taken by mouth: 40 IU of vitamin D3 daily for 20 years to 100,000 IU of vitamin D3 bimonthly for 12 months, or 10,000 IU daily.
For mood disorders, 400-800 IU daily or 100,000 IU weekly has been taken by mouth for up to one month to improve symptoms of depression associated with seasonal affective disorder. In obese patients, 20,000-40,000 IU of vitamin D has been taken by mouth per week for one year.
For multiple sclerosis, 10,000 IU has been taken by mouth daily for 12 weeks. Other doses of vitamin D taken by mouth include 5,000 IU daily (in the form of cod liver oil), progressive weekly increases of vitamin D3 (700 micrograms per week, escalating to 7,000 micrograms per week) plus 1,200 milligrams of calcium.
For muscle weakness or pain, 100,000 IU of calciferol has been taken by mouth daily for 12 months in patients with rheumatoid arthritis.
For osteoporosis, up to 5,714 IU of vitamin D3 or 10,000 IU of vitamin D2 has been taken by mouth daily, or up to 200,000 IU every two months for six months or up to 100,000 IU weekly has been used.
For parasitic infections, 40 IU of vitamin D has been taken by mouth daily for five days.
For physical performance in elderly subjects, 400 IU of vitamin D plus 800 milligrams of calcium has been taken by mouth daily. In older adults, 8,400 IU of vitamin D3 has been taken by mouth weekly for 16 weeks.
For psoriasis, the vitamin D analog calcipotriene has been used topically twice daily.
For respiratory infections, 2,000 IU per kilogram of body weight has been taken by mouth daily for three days.
For rheumatoid arthritis, 50,000 IU of vitamin D has been taken by mouth weekly for 12 weeks.
For senile warts, vitamin D analogs have been applied topically in ointments for up to 12 months.
For tuberculosis, a single dose of 10,000 IU of vitamin D2 has been taken by mouth.
For viral infections, 800 IU of vitamin D has been taken by mouth daily for two years, followed by 2,000 IU of vitamin D daily for 12 months.
For vitiligo, calcipotriol ointment has been used topically twice daily.
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Disclaimer: These statements have been evaluated by the FDA and not meant to treat, mitigate, or cure any disease. This is for educational purposes. Consult with your primary care physician before starting this or any other program.
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What's Dr. Nappi uses personally?
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